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bacteria artificial chromosomes

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Published date: August 17, 2022
  • Location: Doha, Ad Dawhah, Qatar
Bacterial artificial chromosomes (BACs) are large, stably-maintained genomic clones with the capacity to propagate large and unstable foreign DNA fragments in Escherichia coli. In recent years, BAC technology has been also adapted to the manipulation of viral genomes and became an effective alternative to traditional genetic engineering of recombinant oncolytic viruses, especially large DNA viruses such as herpes, vaccinia virus and baculoviruses. Besides, this innovative technology also allows for fast and convenient generation of recombinant adenoviruses particles. BAC also enables the traceless introduction of any mutation using modern tools of bacterial genetics. bacteria artificial chromosomes https://www.creative-biolabs.com/oncolytic-virus/bacterial-artificial-chromosome-bac-technology.htm

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